MAT2A inhibitor|AG-270|CAS 2201056-66-6|DC Chemicals

Cas No.:	2201056-66-6
Chemical Name:	3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Synonyms:	AG-270; AG270; AG 270
SMILES:	O=C1C(C2=CC=C(OC)C=C2)=C(NC3=NC=CC=C3)NC4=C(C5=CCCCC5)C(C6=CC=CC=C6)=NN14
Formula:	C₃₀H₂₇N₅O₂
M.Wt:	489.2165
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	[1]. Zenon Konteatis, et al. Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous MTAP Deletion. J Med Chem. 2021 Apr 8. [2]. Marc L Hyer, et al. The MAT2A inhibitor AG-270 combines with both taxanes and

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