Acolbifene|cas 182167-02-8|DC Chemicals|Price|Buy

Cas No.:	182167-02-8
Chemical Name:	(S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-2H-chromen-7-ol
Synonyms:	EM 652; EM-652; EM652; SCH57068; SCH-57068; SCH 57068; Acolbifene.
SMILES:	OC1=CC=C2C(C)=C(C3=CC=C(O)C=C3)[C@H](C4=CC=C(OCCN5CCCCC5)C=C4)OC2=C1
Formula:	C₂₉H₃₁NO₄
M.Wt:	457.56074
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

acolbifene, also known as EM-652, or SCH-57068, is a selective estrogen receptor modulator (SERM). Acolbifene is currently being studied in the prevention of breast cancer in women at high risk of breast cancer. EM-652 (SCH 57068) and the prodrug EM-800 (SCH57050) which are the most potent of the known antiestrogens. EM-652 is the compound having the highest affinity For the estrogen receptor, including estradiol. It has higher affinity For the ER than ICI 182780, hydroxytamoxifen, raloxifene, droloxifene and hydroxytoremifene. EM-652 has the most potent inhibitory activity on both ER alpha and ER beta compared to any of the other antiestrogens tested. EM-652 was also the most potent inhibitor of the percentage of cycling cancer cells.For the detailed information of Acolbifene, the solubility of Acolbifene in water, the solubility of Acolbifene in DMSO, the solubility of Acolbifene in PBS buffer, the animal experiment (test) of Acolbifene, the cell expriment (test) of Acolbifene, the in vivo, in vitro and clinical trial test of Acolbifene, the EC50, IC50,and Affinity of Acolbifene, Please contact DC Chemicals.

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