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Alagebrium Chloride

  Cat. No.:  DC32320   Featured
Chemical Structure
341028-37-3
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More than 5000 active chemicals with high quality for research!
Field of application
Alagebrium Chloride, identified as ALT711, emerged as a pioneering pharmaceutical candidate developed by Alteon, Inc. It marked the first clinical attempt to address the crosslinks formed by advanced glycation endproducts (AGEs), a key factor in the aging process. By targeting and disrupting these crosslinks, Alagebrium aims to counteract the stiffening of blood vessel walls, a condition linked to hypertension, cardiovascular disorders, and various age-related degenerative issues caused by protein crosslinking. Clinical studies have demonstrated its efficacy in lowering systolic blood pressure and offering therapeutic advantages for individuals with diastolic dysfunction.
Cas No.: 341028-37-3
Chemical Name: Alagebrium chloride
Synonyms: 4,5-Dimethyl-3-(2-oxo-2-phenylethyl)thiazol-3-ium chloride;Alagebrium Chloride;2-(4,5-dimethyl-1,3-thiazol-3-ium-3-yl)-1-phenylethanone,chloride;4,5-Dimethyl-3-(2-oxo-2-phenylethyl)-thiazol-3-ium chloride;Alagebrium chloride (USAN);ALT-711;UNII-79QS8K2877;4,5-Dimethyl-3-(2-oxo-2-phenylethyl)thiazolium Chloride;2-(4,5-Dimethyl-1,3-thiazol-3-yl)-1-phenyl-ethanone chloride;Thiazolium, 4,5-dimethyl-3-(2-oxo-2-phenylethyl)-, chloride;4,5-Dimethyl-3-(2-oxo-2-phenyl)-chloride;79QS8K2877;AK113418;4,5-dimethyl-3-(2-oxo-2-phenylethyl)-1,3-thiazol-3-ium chloride;ALT711;Alagebrium chloride [USAN:INN];MLS006010880;BC;2-(4,5-dimethylthiazol-3-ium-3-yl)-1-phenyl-ethanone chloride;FT-0617203;ALT-711,ALAGEBRIUM;A822078;ALAGEBRIUM CHLORIDE [USAN];HY-106024B;CS-0024653;SCHEMBL33828;4,5-dimethyl-3-(2-oxo-2-phenylethyl)-thiazolium chloride;ALAGEBRIUM CHLORIDE [INN];BCP17598;D03206;CHEMBL2107309;AC-3507;341028-37-3;DTXSID60955648;Q25717;ALAGEBRIUM CHLORIDE [MI];AKOS016009967;DS-6264;AMY38142;THIAZOLIUM, 4,5-DIMETHYL-3-(2-OXO-2-PHENYLETHYL), CHLORIDE;MFCD09027398;2-(4,5-dimethyl-1,3-thiazol-3-ium-3-yl)-1-phenylethanone;chloride;4,5-Dimethyl-3-(2-oxo-2-phenyl)-thiazoliumchloride;SMR004701797;341028-37-3 (chloride);chlorure d'alagebrium;cloruro de alagebrio;4,5-Dimethyl-3-(2-oxo-2-phenylethyl)thiazol-3-ium Chloride; ALT 711;alagebrium chloridum;GLXC-01782;A3166
SMILES: [Cl-].S1C([H])=[N+](C([H])([H])C(C2C([H])=C([H])C([H])=C([H])C=2[H])=O)C(C([H])([H])[H])=C1C([H])([H])[H]
Formula: C13H14ClNOs
M.Wt: 267.7744
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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