Alemtuzumab|CAS 216503-57-0|DC Chemicals

Cas No.:	216503-57-0
pH value:	Corresponds to reference standard： PASS
Non-reduced CE-SDS:	98.5%
SEC-HPLC:	99.4%
Isoelectric Point:	Corresponds to reference standard
Bacterial Endotoxins Test:	＜1 EU/ml
Exogenous Residual DNA:	＜1 pg/mg
Residual protein A:	＜1 ng/mg
Biological Activity:	Compared with standard, the range ofbiological activity is 91%
Osmolality:	Corresponds to reference standard: PASS
Peptide mapping:	Corresponds to reference standard: PASS
N-terminal sequence:	Corresponds to reference standard:PASS

Description:

Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein,CD52. The Campath-1H antibody is an IgG1 kappa with human variable framework and constant regions, and complementarity-determining regions from a murine (rat) monoclonal antibody (Campath-1G). Campath is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium containing neomycin.

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