Alstonine|CAS 642-18-2|DC Chemicals

Cas No.:	642-18-2
Chemical Name:	Alstonine
SMILES:	COC(C1=CO[C@@H](C)[C@@]2([H])[C@]1([H])CC3=[N+](C2)C=CC4=C3[N-]C5=C4C=CC=C5)=O
Formula:	C₂₁H₂₀N₂O₃
M.Wt:	348.40
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

Cat. No.	Product name	Field of application
DC47407	Antimalarial agent 3	Antimalarial agent 3 shows nanomolar antiplasmodial activity (IC50 = 0.035 μM) and has a very high selectivity index with respect to mammalian cells.
DC47406	Antileishmanial agent-2	Antileishmanial agent-2 shows submicromolar antileishmanial activity (IC50 = 0.29 μM) and a very high selectivity index with respect to mammalian cells.
DC47405	Antimalarial agent 2	Antimalarial agent 2 is a novel orally efficacious antimalarials that suggests a fast in vitro killing profile.
DC47404	TCMDC-125431	TCMDC-125431 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
DC47403	TCMDC-136230	TCMDC-136230 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
DC47402	TCMDC-125457	TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.
DC47401	Antileishmanial agent-1	Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC50 = 15.52 μM) and intracellular amastigotes (IC50 = 4.10 μM).
DC47400	BRD5018	BRD5018 is an antimalarial agent.
DC47397	Carpaine	Carpaine is an alkaloid isolated from Carica papaya Linn with anti-thrombocytopenic activity, exhibits potent activity in sustaining platelet counts with no acute toxicity. Carpaine has anti-plasmodial activity to prevent malaria.
DC47107	14-Deoxy-11-oxoandrographolide	14-Deoxy-11-oxoandrographolide is an antileishmanial agent. 14-Deoxy-11-oxoandrographolide inhibits the replication of heal chikungunya virus (CHIKV) and can be used for CHIKV infection research.