Cdk1/2 Inhibitor III | Cdk1/2 Inhibitor

Cas No.:	443798-55-8
Chemical Name:	Cdk1/2 Inhibitor III
SMILES:	S=C(N1N=C(NC2=CC=C(S(=O)(N)=O)C=C2)N=C1N)NC3=C(F)C=CC=C3F
Formula:	C₁₅H₁₃F₂N₇O₂S₂
M.Wt:	425.433
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	Cdk1/2 Inhibitor III is a selective Cdk1/2 inhibitor, with an IC50 of 2.1 μM for CDK1/cyclin B[1].
Target:	Cdk1/cyclin B:2.1 μM (IC50)
In Vitro:	Cdk1/2 Inhibitor III has weak CDK1 and cellular antiproliferative potencies[1].
References:	[1]. Lin R, et al. Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: synthesis and evaluation of biological activities. J Med Chem. 2005 Jun 30;48(13):4208-11.

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