GAK inhibitor 49 |CAS 319492-82-5|DC Chemicals

Cas No.:	319492-82-5
Chemical Name:	GAK inhibitor 49
Synonyms:	4-QUINOLINAMINE, 6,7-DIMETHOXY-N-(3,4,5-TRIMETHOXYPHENYL)-;GAK inhibitor 49
SMILES:	COC1C(OC)=CC2=C(C(NC3C=C(OC)C(OC)=C(OC)C=3)=CC=N2)C=1
Formula:	C₂₀H₂₂N₂O₅
M.Wt:	370.399
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

GAK inhibitor 49 is a potent, selective, ATP-competitive inhibitor of cyclin G-associated kinase (GAK, cell IC50=56 nM) with favourable NAK family selectivity (AAK1, STK16, BMP2K); shows binding to only GAK and RIPK2 in an unbiased MIB/MS experiment in cell lysate.

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