VHL-2|VHL ligand 2

Cas No.:	1631137-31-9
Chemical Name:	(2S,4R)-1-((S)-2-((S)-2-acetamido-3-phenylpropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Synonyms:	VHL ligand 2
SMILES:	N(C(=O)[C@H](NC(=O)[C@H](NC(=O)C)CC1=CC=CC=C1)C(C)(C)C)1C[C@@H](O)C[C@@H]1C(NCC1=CC=C(C2SC=NC=2C)C=C1)=O
Formula:	C₃₃H₄₁N₅O₅S
M.Wt:	619.781
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A VHL ligand for PROTAC.

Cat. No.	Product name	Field of application
DC47587	cIAP1 ligand 4	cIAP1 ligand 4 is a ligand for E3 ligase that can be used in the synthesis of PROTACs.
DC47586	(R)-Pomalidomide-pyrrolidine	(R)-Pomalidomide-pyrrolidine, a CRBN ligand, can be connected to the ligand for protein by a linker to form PROTACs.
DC47217	Pomalidomide-7-NH2	Pomalidomide-7-NH2 is the Pomalidomide-based cereblon ligand used in the recruitment of CRBN protein. Pomalidomide-7-NH2 can be connected to the ligand for protein by a linker to form PROTACs.
DC47215	Thalidomide-4-C3-NH2 hydrochloride	Thalidomide-4-C3-NH2 hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-C3-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs.
DC47208	Pomalidomide-5-OH	Pomalidomide-5-OH (5-hydroxy pomalidomide) is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTAC.
DC47143	Thalidomide-5-methyl	Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.
DC47142	Thalidomide-5-propoxyethanamine	Thalidomide-5-propoxyethanamine is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.
DC46963	Thalidomide-benzo	Thalidomide-benzo hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-benzo can be connected to the ligand for protein by a linker to form PROTACs.
DC46962	Thalidomide-5-propargyne-NH2 hydrochloride	Thalidomide-5-propargyne-NH2 hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-propargyne-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs.
DC46961	Thalidomide-5-PEG2-Cl	Thalidomide-5-PEG2-Cl is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-PEG2-Cl can be connected to the ligand for protein by a linker to form PROTACs.