dBRD9 |CAS 2170679-45-3|DC Chemicals

Cas No.:	2170679-45-3
Chemical Name:	2-((2,6-dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)(methyl)amino)-N-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)acetamide
Synonyms:	dBRD 9
SMILES:	C(NCCOCCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O)(=O)CN(CC1=C(OC)C=C(C2C3C(C(=O)N(C)C=2)=CN=CC=3)C=C1OC)C
Formula:	C₄₀H₄₅N₇O₁₀
M.Wt:	783.839
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

dBRD9 is a PROTAC that bridge the BRD9 bromodomain and the cereblon E3 ubiquitin ligase complex; exhibits markedly enhanced potency compared to parental ligands (10-100 fold).

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