MT-031|MT 031;MT031

Cas No.:	1802158-63-9
Chemical Name:	(S)-Ethyl-methyl-carbamic acid 3-[1-(methyl-prop-2-ynyl-amino)-ethyl]-phenyl ester
Synonyms:	MT 031;MT031
SMILES:	C(OC1=CC=CC([C@H](N(C)CC#C)C)=C1)(=O)N(CC)C
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A potent, brain penetrant, dual MAO-A and AChE inhibitor that shows neuroprotective effects both in vitro and in vivo; inhibits H2O2-induced neurotoxicity in human neuroblastoma SH-SY5Y cells, and antagonizes scopolamine-induced memory and cognitive impairments in mice; upregulates mRNA expression levels of Bcl-2, the neurotrophic factors and the anti-inflammatory cytokine, Ntrk, and down-regulates the mRNA expression levels of IL-6 in scopolamine-induced mice.

Cat. No.	Product name	Field of application
DC47566	(S)-Salsolidine	(S)-Salsolidine is a weak monoamine oxidase (MAO) inhibitor (Ki=63 μM). The R enantiomer of Salsolidine is more potent than the S form (Ki=26 μM).
DC47565	Ladostigil hemitartrate	Ladostigil (TV-3326) hemitartrate is a dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO), with an IC50 of 37.1 and 31.8 μM for MAO-B and AChE, reapectively. Ladostigil hemitartrate could increase cholinergic transmission, prevent the formation of ROS or their actions and be used for the research of depression and Alzheimer's disease.
DC47564	(+)-Cinchonaminone	(+)-Cinchonaminone shows monoamine oxidase (MAO) inhibitory activity.
DC47563	MAO-B-IN-2	MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC50 values of 0.51 and 7.00 μM, respectively.
DC47233	Kynuramine dihydrochloride	Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase.
DC47199	Salsolidine hydrochloride	Salsolidine hydrochloride, a tetrahydroisoquinoline alkaloid, acts as a stereoselective competitive MAO A (monoamine oxidase A) inhibitor.
DC47102	SSAO inhibitor-1	SSAO inhibitor-1 is a semicarbazide-sensitive amine oxidase (SSAO) inhibitor. SSAO inhibitor-1 has anti-inflammatory activity and can be used for liver diseases research.
DC46484	1-Methyl-2-undecyl-4(1H)-quinolone	1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS.
DC46446	Methyl citrate	Methyl citrate is a Monoamine oxidase B (MAO-B) inhibitor (IC50=0.23 mM). Methyl citrate is isolated from the fruits of Opuntia ficus-indica var. saboten Makino.
DC44964	Glicoricone	Glicoricone, a phenolic compound, is isolated from a species of licorice. Glicoricone is an inhibitor of monoamine oxidase (MAO), with an IC50 of 140 μM. Glicoricone binds to estrogen receptor (ER) and shows estrogen antagonist activity.