| Cas No.: | 775294-71-8 |
| Chemical Name: | 3-(2-(([1,1'-biphenyl]-4-ylmethyl)amino)-1-hydroxyethyl)phenol |
| Synonyms: | AC 73;AC73 |
| SMILES: | C(O)1=CC=CC(C(O)CNCC2=CC=C(C3=CC=CC=C3)C=C2)=C1 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A novel, specific CD147 inhibitor that can specifically disrupt CD147 dimerization, inhibits the motility and invasion of HCC cells (IC50=7-10 uM); inhibits the motility and invasion of typical HCC cells, but not HCC cells that lacked the CD147 gene, reduces HCC metastasis by suppressing MMP-2 via down-regulation of the CD147/ERK1/2/STAT3 signaling pathway; attenuates progression in an orthotopic nude mouse model of liver metastasis |

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