| Cas No.: | 1219104-20-7 |
| Chemical Name: | (7aS,12aS)-7,7a-dihydro-5H-benzo[g]benzofuro[3,2-c]chromene-5,13(12aH)-dione |
| Synonyms: | LQB 118;LQB118 |
| SMILES: | C1OC2=C(C(=O)C3=CC=CC=C3C2=O)[C@@]([H])2OC3=CC=CC=C3[C@]12[H] |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | An orally active pterocarpanquinone that exhibits antitumoral and antileishmanial activity both in vitro and in vivo; induces apoptosis in cells derived from chronic myeloid leukemia patients, exhibiting multifactorial drug resistance phenotype such as P-glycoprotein, MRP1 and p53 overexpression; shows activity active against intracellular amastigotes of L. amazonensis with IC50 of 1.4 uM, inhibits parasite growth in L.amazonensis-infected BALB/c mice. |

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