PF 750|cas 959151-50-9|DC Chemicals

Cas No.:	959151-50-9
Chemical Name:	PF 750
Synonyms:	PF 750;N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide;PF-750;Nisoxetine hydrochloride
SMILES:	O=C(N1CCC(CC2C=NC3=C(C=CC=C3)C=2)CC1)NC1=CC=CC=C1
Formula:	C₂₂H₂₃N₃O
M.Wt:	345.437525033951
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme’s active site serine nucleophile[1].
Target:	IC50: 16.2-595 nM (FAAH)[1].
References:	[1]. Ahn K, et al. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry. 2007 Nov 13;46(45):13019-30.

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