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NRX-103094

  Cat. No.:  DC20251   Featured
Chemical Structure
2763260-36-0
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More than 5000 active chemicals with high quality for research!
Field of application
NRX-103094 is a potent enhancer of the interaction between β-catenin and its cognate E3 ligase, SCFβ-TrCP. It significantly strengthens the binding of the pSer33/Ser37 β-catenin peptide to β-TrCP, exhibiting an EC50 of 62 nM and a Kd of 0.6 nM.
Cas No.: 2763260-36-0
Chemical Name: Benzoic acid, 3-[[[4-[(2,6-dichlorophenyl)thio]-1,2-dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinyl]carbonyl]amino]-
Synonyms: Benzoic acid, 3-[[[4-[(2,6-dichlorophenyl)thio]-1,2-dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinyl]carbonyl]amino]-;NRX-103094
SMILES: C(O)(=O)C1=CC=CC(NC(C2=C(SC3=C(Cl)C=CC=C3Cl)C=C(C(F)(F)F)NC2=O)=O)=C1
Formula: C20H11Cl2F3N2O4S
M.Wt: 503.278552293777
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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