TBBz|cas 577779-57-8|DC Chemicals

Cas No.:	577779-57-8
Chemical Name:	4,5,6,7-Tetrabromobenzimidazole
Synonyms:	4,5,6,7-Tetrabromobenzimidazole;4,5,6,7-tetrabromo-1H-benzimidazole;4,5,6,7-Tetrabromobe;tbbz;2oxy;4,5,6,7-Tetrabrom-1H-benzimidazol
SMILES:	BrC1C2=C(N=CN2)C(Br)=C(Br)C=1Br
Formula:	C₇H₂Br₄N₂
M.Wt:	433.720178127289
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A potent, selective and ATP-competitive CK2 inhibitor with Ki of 0.5-1 uM; weakly inhibits CK1 (about 100-fold less potent), and has no activity for PKA and PKC; decreases the activity of GBM-initiating cell regulator β-catenin, reduces cell growth, decreases tumor size, and increases survival rates in GBM xenograft mouse models.

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