ALE-0540 |CAS 234779-34-1|DC Chemicals

Cas No.:	234779-34-1
Chemical Name:	1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-((2-hydroxyethyl)amino)-5-nitro-
Synonyms:	1R1L47BXMJ;1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-((2-hydroxyethyl)amino)-5-nitro-;2-(2-hydroxyethylamino)-5-nitrobenzo[de]isoquinoline-1,3-dione;1,3-dione;Oprea1_821712;ALE0540;ALE 0540;BDBM50111443;Q27252774;2-(2-Hydroxy-ethylamino)-5-nitro-benzo[de]isoquinoline-
SMILES:	O=C1C2=CC(=CC3=CC=CC(C(N1NCCO)=O)=C23)[N+](=O)[O-]
Formula:	C₁₄H₁₁N₃O₅
M.Wt:	301.254243135452
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

ALE-0540 is a nerve growth factor (NGF) antagonist that inhibits the binding of NGF to TrkA or both p75 and TrkA with IC50 of 5.88 and 3.72 uM, respectively; produces antiallodynic actions in models of neuropathic pain.PainDiscontinued

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