PF-06928215 |CAS 2378173-15-8|DC Chemicals

Cas No.:	2378173-15-8
Chemical Name:	PF-06928215
Synonyms:	(1R,2S)-2-{[(7-Hydroxy-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl)carbonyl]amino}cyclohexanecarboxylic ac;PF-06928215;CID 137300622;(1R,2S)-2-[(7-oxo-5-phenyl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]cyclohexane-1-carboxylic acid;(1R,2S)-2-[[(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl)carbonyl]amino]-cyclohexanecarboxylic acid;(1R,2S)-2-[(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]cyclohexane-1-carboxylic acid;GTPL11324;BDBM50250108;(1R,2S)-2-(7-Hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamido)cyclohexanecarboxylic ac
SMILES:	O([H])C([C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(C1=C([H])N([H])N2C(C([H])=C(C3C([H])=C([H])C([H])=C([H])C=3[H])N=C21)=O)=O)=O
Formula:	C₂₀H₂₀N₄O₄
M.Wt:	380.3972
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

PF-06928215 (PF06928215) is a high affinity Cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 200 nM, IC50 of 4.9 uM.

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