| Cas No.: | 1881233-39-1 |
| Chemical Name: | PI4KIIIbeta-IN-10 |
| Synonyms: | PI4KIIIbeta-IN-10;N-(5-(3-(N-(4-hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)pivalamide;N-[5-[3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide;PI4KIII beta inhibitor 1;PI4KIII-beta-inhibitor-1;BDBM50160075;AT14171;A908340 |
| SMILES: | S(C1=C(C([H])=C([H])C(=C1[H])C1=C(C([H])([H])[H])N=C(N([H])C(C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=O)S1)OC([H])([H])[H])(N([H])C1C([H])=C([H])C(=C([H])C=1[H])O[H])(=O)=O |
| Formula: | C22H25N3O5S2 |
| M.Wt: | 475.5810 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A potent and selective type III phosphatidylinositol 4-kinase (PI4KIIIβ) inhibitor with IC50 of 3.6 nM; displays >200-fold selectivity over class I and class III PI3Ks; shows antiviral activity against hepatitis C virus with IC50 of 1.3 uM, with low cytotoxicity (CC50>32 uM). |

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