| Cas No.: | 24699-16-9 |
| Chemical Name: | 4-beta-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one |
| SMILES: | OC[C@H]1O[C@@H](C2=C(O)C=C(O)C3C(C4=CC(O)=C(O)C=C4OC2=3)=O)[C@H](O)[C@@H](O)[C@@H]1O |
| Formula: | C19H18O11 |
| M.Wt: | 422.3396 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Isomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM, also blocks calcium channel; also effectively blocks the EphA4-dependent signaling in hippocampal neurons, reduces the EphA4 activity effectively in the hippocampus of APP/PS1 transgenic mice after oral administration, restores the impaired long-term potentiation in transgenic mouse models of AD. |

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