ONO-1301| CAS 176391-41-6

Cas No.:	176391-41-6
Chemical Name:	({5-[2-({[(1E)-phenyl(pyridin-3-yl)methylidene]amino}oxy)ethyl]-7,8-dihydronaphthalen-1-yl}oxy)acetic acid
Synonyms:	({5-[2-({[(1E)-phenyl(pyridin-3-yl)methylidene]amino}oxy)ethyl]-7,8-dihydronaphthalen-1-yl}oxy)acetic acid;({5-[2-({[(E)-phenyl(pyridin-3-yl)methylidene]amino}oxy)ethyl]-7,8-dihydronaphthalen-1-yl}oxy)acetic acid;acetic acid, 2-[[7,8-dihydro-5-[2-[[[(1E)-phenyl-3-pyridinylmethylene]amino]oxy]ethyl]-1-naphthalenyl]oxy]-;7,8-dihydro-5-[(e)-[[α-(3-pyridyl)benzylidene]aminooxy]ethyl]-1-naphthyloxy]acetic acid
SMILES:	C1(/C(=N/OCCC2=CCCC3=C2C=CC=C3OCC(O)=O)/C2=CC=CN=C2)C=CC=CC=1
Formula:	C₂₆H₂₄N₂O₄
M.Wt:	428.47976
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A stable, orally active, non-prostanoid prostacyclin I2 (PGI2) mimetic and prostacyclin agonist with inhibitory activity against thromboxane A2 synthase; suppresses the elevation of protein excretion into urine in rats, attenuates the development of bleomycin-induced pulmonary fibrosis and improves survival in bleomycin mice.ThrombosisDiscontinued

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