| Cas No.: | 1122147-66-3 |
| Chemical Name: | 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one |
| Synonyms: | SN 79;SN-79 |
| Formula: | C23H26FN3O3 |
| M.Wt: | 411.477 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A potent, orally active sigma receptor antaognist with Ki of 27 and 7 nM for σ1 and σ2, respectively; also exhibits moderate affinity for serotonin transporters and norepinephrine transporters, displays a moderate affinity for 5-HT2 receptors and negligible affinity, does not inhibit major cytochrome P450 enzymes; significantly attenuates cocaine-induced convulsions and locomotor activity in mice, also significantly attenuates the development and expression of the sensitized response to repeated cocaine exposures. |

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