AICP| CAS 861213-66-3

Cas No.:	861213-66-3
Chemical Name:	(2R)-2-Amino-3-[[4-(2-ethylphenyl)-1H-indole-2-carbonyl]amino]propanoic acid
Synonyms:	(2R)-2-Amino-3-[[4-(2-ethylphenyl)-1H-indole-2-carbonyl]amino]propanoic acid
SMILES:	O=C(C1=CC2=C(C=CC=C2C2C=CC=CC=2CC)N1)NC[C@H](C(=O)O)N
Formula:	C₂₀H₂₁N₃O₃
M.Wt:	351.399044752121
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A potent, selective GluN2C-selective NMDA receptor glycine site superagonist with EC50 of 1.7 nM at GluN1/2C; AICP is a full agonist at GluN1/2A (100% response compared with glycine), a partial agonist at GluN1/2B and GluN1/2D (10% and 27%, respectively), and a highly efficacious superagonist at GluN1/2C receptors (353%); selectively enhances responses from recombinant GluN1/2C receptors in the presence of physiological glycine concentrations.

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