| Cas No.: | 193979-75-8 |
| Chemical Name: | N,N-Dipropyl-2-(4-chlorophenyl)-6,8-dichloro-imidazo[1,2-a]pyridine-3-acetamide |
| Synonyms: | CB-34;CB 34 |
| SMILES: | CCCN(CCC)C(=O)CC1N2C(C(Cl)=CC(Cl)=C2)=NC=1C3=CC=C(Cl)C=C3 |
| Formula: | C21H22Cl3N3O |
| M.Wt: | 438.777 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A potent, selective translocator protein 18 kDa (TSPO/PBR) agonist with IC50 of 2.59 and 1.03 nM in competing with [3H]-PK11195 for binding to membrane preparations from rat cerebral cortex and ovary, respectively; does not show any affinity for central benzodiazepine receptors, has little or no marked effects on GABA-evoked Cl- currents; induces a dose-dependent increase in the concentrations of neuroactive steroids in plasma and brain, stimulate brain steroidogenesis in vivo. |

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