Roseoflavin| CAS 51093-55-1|DC Chemicals

Cas No.:	51093-55-1
Chemical Name:	Riboflavin,8-demethyl-8-(dimethylamino)-
Synonyms:	Riboflavin,8-demethyl-8-(dimethylamino)-;Roseoflavin;8-(dimethylamino)-7-methyl-10-(2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4-dione;7-Methyl-8-dimethylamino-10-(1'-D-ribityl)isoalloxazin;8-(dimethylamino)-7-methyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione;8-demethyl-8-(dimethylamino)riboflavin;8-dimethylamino-7-methyl-10-D-ribitol-1-yl-10H-benzo[g]pteridine;8-Dimethylaminoriboflavin;Riboflavin,8-demethyl-8-(dimethylamino);Roseoflavine;8-Demethyl-8-(dimethylamino)-riboflavin
SMILES:	OCC(C(C(CN1C2=NC(NC(=O)C2=NC2C=C(C(=CC1=2)N(C)C)C)=O)O)O)O
Formula:	C₁₈H₂₃N₅O₆
M.Wt:	405.405123949051
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	Roseoflavin, a natural pigment originally isolated from Streptomyces davawensis, is an antimetabolite analog of Riboflavin and flavin mononucleotide that has antimicrobial properties[1].
In Vitro:	Roseoflavin, a chemical analog of flavin mononucleotide (FMN) and riboflavin that has antimicrobial activity, can directly bind to FMN riboswitch (Kd~100 nM) aptamers and downregulate the expression of an FMN riboswitch-lacZ reporter gene in B. subtilis[1].
References:	[1]. Lee ER, et al. Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression. RNA Biol. 2009;6(2):187-194.

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