| Cas No.: | 534579-04-9 |
| Chemical Name: | ethyl (Z)-2-(acetylimino)-1-cyclohexyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate |
| Synonyms: | BC54 |
| Formula: | C22H24N4O4 |
| M.Wt: | 408.458 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A potent and biologically-active PDE4/7 inhibitor with IC50 of 50-100 nM for PDE4A/B/D, and 140 nM for both PDE7A/B; showed only modest activity (IC50=3 uM) against PDE2A and PDE11A, and little to no activity (IC50 >10 uM) against PDE1C/3B/5A /8A/9A/10A; displays exceptional anti-inflammatory activity and induces apoptosis in CLL cells. |

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