ARM-1| CAS 68729-05-5|DC Chemicals

Cas No.:	68729-05-5
Chemical Name:	4-(4-Benzylphenyl)-1,3-thiazol-2-amine
Synonyms:	Arm1;4-(4-benzylphenyl)-1,3-thiazol-2-amine;1V6;4l2l;ARM-1;Oprea1_716646;Oprea1_110562;BBL020883;STK893589;BDBM50197084;4-(4-benzylphenyl) thiazol-2 amine;2-Thiazolamine, 4-[4-(phenylmethyl)phenyl]-;Q27452475
SMILES:	S1C(N([H])[H])=NC(=C1[H])C1C([H])=C([H])C(=C([H])C=1[H])C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H]
Formula:	C₁₆H₁₄N₂S
M.Wt:	266.3608
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM; selectively blocks conversion of LTA4 into LTB4, sparing the enzyme's anti-inflammatory aminopeptidase activity; represents a new class of LTA4 hydrolase inhibitor that holds promise for improved anti-inflammatory properties.

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