N6-Cyclohexyladenosine| CAS 36396-99-3|DC Chemicals

Cas No.:	36396-99-3
Chemical Name:	(2R,3R,4S,5R)-2-(6-(Cyclohexylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Synonyms:	(2R,3R,4S,5R)-2-(6-(Cyclohexylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;Adenosine,N-cyclohexyl-;CHA;N6-Cyclohexyladenosine;Cyclohexyladenosine;N-Cyclohexyladenosine
SMILES:	C1(NC2N=CN=C3C=2N=CN3C2C(O)C(O)C(CO)O2)CCCCC1
Formula:	C₁₆H₂₃N₅O₄
M.Wt:	349.384923219681
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	N6-Cyclohexyladenosine is a selective A1 receptor agonist (EC50 = 8.2 nM).
Target:	A1 receptor
In Vivo:	N6-Cyclohexyladenosine exerts anticonvulsant effects and protects against neuronal death. CHA was also found to inhibit the pressor effects of lumbar sympathetic nerve stimulation in rats.
References:	[1]. Asghari AA, et al. Adenosine A1 receptor agonist, N6-cyclohexyladenosine, protects myelin and induces remyelination in an experimental model of rat optic chiasm demyelination; electrophysiological and histopathological studies. J Neurol Sci. 2013 Feb 15;3

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