| Cas No.: | 901-47-3 |
| Chemical Name: | L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester |
| Synonyms: | Tosyl-L-arginine methyl ester |
| SMILES: | COC(=O)C(CCCNC(=N)N)NS(C1C=CC(C)=CC=1)(=O)=O |
| Formula: | C14H22N4O4S |
| M.Wt: | 342.4139 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A small molecule anaphase-promoting complex/cyclosome (APC/C) inhibitor that binds to the APC preferentially suppresses APC/C(Cdc20) rather than APC/C(Cdh1); inhibits cyclin proteolysis in mitotic Xenopus egg extract with IC50 of 12 uM; promotes Cdc20 autoubiquitination, blocks cyclin degradation in interphase extract. |

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