| Cas No.: | 138154-55-9 |
| Chemical Name: | 5-((2-(diethylamino)ethyl)amino)-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one dihydrochloride |
| Synonyms: | XLS-002;Symadex;Imidacrine;Imidazoacridone |
| Formula: | C20H26Cl2N4O3 |
| M.Wt: | 441.35 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | An imidazoacridinone analogue with potent in vivo antitumour activity, inhibits the catalytic activity of Topoisomerase II; induces p53-dependent senescence or p53-independent apoptosis and sensitizes cancer cells to radiation, also induces autophagy in a non-p53-dependent manner, and effectively improves the radiosensitivity of a panel of cancer cell lines. |

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