RO 5256390| CAS 1043495-96-0

Cas No.:	1043495-96-0
Chemical Name:	RO5256390 free base
Synonyms:	(S)-4-((S)-2-PHENYLBUTYL)-4,5-DIHYDROOXAZOL-2-AMINE;RO 5256390;TAAR1;(S)-4-((S)-2-phenyl-butyl)-4,5-dihydro-oxazol-2-ylamine;RO5256390;IXDKFUBXESWHSL-JQWIXIFHSA-N;BDBM109524;RO5256390, >=98% (HPLC);US8604061, 292;2-Oxazolamine, 4,5-dihydro-4-[(2S)-2-phenylbutyl]-, (4S)-
SMILES:	O1C(N)=N[C@H](C1)C[C@@H](C1C=CC=CC=1)CC
Formula:	C₁₃H₁₈N₂O
M.Wt:	218.3
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A highly potent, selective and orally bioavailable trace amine-associated receptor 1 (TRRA1) full agonist with EC50 of 18 nM, >500-fold selectivity over human adrenergic α2A receptor; blocks psychostimulant-induced hyperactivity and produces a brain activation pattern reminiscent of the antipsychotic drug olanzapine in vivo, does not induce catalepsy or weight gain.

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