| Cas No.: | 2215102-35-3 |
| Synonyms: | CCC 07-01;CCC 0701 |
| Formula: | C90H93ClN30O16 |
| M.Wt: | 1886.378 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | CCC07-01 (CCC 0701) is a novel alkylating compound that is capable of disrupting expression of PD-1, PD-L1 and CTLA-4 genes with IC50 of 15, 10 and 5 nM in cell-base assays; significantly suppresses PD-1, PD-L1 and CTLA-4 mRNA levels in several cell lines, CCC07-01 is sufficiently lipophilic that enhaced the inhibitory effect of CD94-NKG-2A receptor expressed on subsets of NK cells γδ and CD8+ T cells. |

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