| Cas No.: | 1115270-63-7 |
| Chemical Name: | Methyl 6-amino-6-deoxy-2,3-di-O-tetradecyl-a-D-glucopyranoside |
| Synonyms: | IAXO102 |
| Formula: | C35H71NO5 |
| M.Wt: | 585.955 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | IAXO-102 is a novel selective TLR4 antagonist, negatively regulates non-hematopoietic TLR4 signalling and inhibits experimental AAA development; inhibits MAPK and p65 NF-kB phosphorylation associated with down regulation of the expression of TLR4 and TLR4 dependent proinflammatory proteins, decreases Angiotensin II-induced aortic expansion, rupture and incidence of abdominal aortic aneurysm (AAA). |

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