| Cas No.: | 2219362-20-4 |
| Chemical Name: | D-Ala-D-Ala-Leu-Pro-Ile-Pro-Leu-Asp-Gln-Thr-D-Ala-D-Ala-NH2 |
| Synonyms: | SPX101;SPX 101 |
| Formula: | C53H90N14O16 |
| M.Wt: | 1179.385 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | SPX-101 is a specific, peptide mimetic promoter of epithelial sodium channel (ENaC) internalization, binds selectively to ENaC and promotes internalization of the α-, β-, and γ-subunits; promotes durable reduction of ENaC membrane concentration, increases mucus transport in the β-ENaC mouse model as well as the sheep model of CF.FibrosisPhase 2 Clinical |

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