LY305| CAS 1430230-83-3

Cas No.:	1430230-83-3
Chemical Name:	2-Chloro-4-{[(1r,2r)-2-Hydroxy-2-Methylcyclopentyl]amino}-3-Methylbenzonitrile
Synonyms:	2-Chloro-4-{[(1r,2r)-2-Hydroxy-2-Methylcyclopentyl]amino}-3-Methylbenzonitrile;2-Chloro-4-(((1R,2R)-2-hydroxy-2-methylcyclopentyl)amino)-3-methylbenzonitrile;2-chloro-4-[[(1R,2R)-2-hydroxy-2-methylcyclopentyl]amino]-3-methylbenzonitrile;BDBM50145863;Q27455402;2-Chloro-4-[[(1R,2R)-2-hydroxy-2-methyl-cyclopentyl]amino]-3-methyl-benzonitrile;51Y
SMILES:	ClC1=C(C#N)C=CC(=C1C)N[C@@H]1CCC[C@@]1(C)O
Formula:	C₁₄H₁₇ClN₂O
M.Wt:	264.750582456589
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM, demonstrates potent agonist activity in the aforementioned C2C12 cellular assay (EC50=0.499 nM); displays little to no affinity for GR, PR and MR (Ki>800 nM); shows the desired muscle and prostate effects in a preclinical ORX rat model.

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