| Cas No.: | 859724-30-4 |
| Chemical Name: | (R)-1-(8-((2-phenylpropanoyl)oxy)octyl)pyridin-1-ium bromide |
| Synonyms: | MRS2481 |
| Formula: | C22H30BrNO2 |
| M.Wt: | 420.391 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | MRS 2481 is a potent, reversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity; also is a potent inhibitor of TNFα-induced phosphorylation and proteosomal destruction of IκBα, inhibits both NFκB and AP-1 signaling on the IL-8 promoter (IC50=1.8 uM); blocks TNFα-activated phosphorylation of JNK, the c-JUN kinase. |

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