| Cas No.: | 956128-08-8 |
| Chemical Name: | 5-(3-(dimethylamino)phenoxy)-N-phenylpyrimidin-2-amine |
| Synonyms: | TDI2760 |
| Formula: | C18H18N4O |
| M.Wt: | 306.369 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | TDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction (IC50=1.67 uM) but also retains potency toward the Aβ42 aggregation inhibition process; restores the Aβ42-induced decrease in fibrin clot turbidity without affecting normal clotting in an in vitro clotting assay, effectively inhibits Aβ42 fibrillization and modulates Aβ42-induced contact system activation. |

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