Presatovir| CAS 1353625-73-6 |DC Chemicals

Cas No.:	1353625-73-6
Chemical Name:	Presatovir
Synonyms:	Presatovir;GS-5806;N-[2-[[(2S)-2-[5-[(3S)-3-Amino-1-pyrrolidinyl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]-1-piperidinyl]carbonyl]-4-chlorophenyl]methanesulfonamide;GS 5806;BCP17831;N-[2-[(2S)-2-[5-(3-Aminopyrrolidin-1-yl)-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl;9628AJ27JA;Presatovir [USAN:INN];GS5806;Presatovir (USAN/INN);DB12165;Methanesulfonamide, N-(2-(((2S)-2-(5-((3S)-3-amino-1-pyrrolidinyl)-6-methylpyrazolo(1,5-a)pyrimidin-2-yl)-1-piperidinyl)carbonyl)-4-chlorophenyl)-;D11216;Q27271846;N-(2-((S)-2-(5-((S)-3-aminopyrrolidin-1-yl)-6-methylpyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chloroph
SMILES:	ClC1C([H])=C([H])C(=C(C=1[H])C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1C([H])=C2N=C(C(C([H])([H])[H])=C([H])N2N=1)N1C([H])([H])C([H])([H])[C@@]([H])(C1([H])[H])N([H])[H])=O)N([H])S(C([H])([H])[H])(=O)=O
Formula:	C₂₄H₃₀ClN₇O₃S
M.Wt:	532.0581
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Presatovir (GS-5806) is a novel, orally bioavailable RSV fusion inhibitor with mean EC50 of 0.43 nM against a panel of 75 RSV A and B clinical isolates; exhibits low cytotoxicity in human cell lines and primary cell cultures (selectivity > 23,000-fold); shows excellent antiviral efficacy in the cotton rat model of RSV infection. RSV Infection Phase 2 Clinical

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