PF-06650833| CAS 1817626-54-2|DC Chemicals

Cas No.:	1817626-54-2
Chemical Name:	6-Isoquinolinecarboxamide, 1-[[(2S,3S,4S)-3-ethyl-4-fluoro-5-oxo-2-pyrrolidinyl]methoxy]-7-methoxy-
Synonyms:	PF06650833;PF 06650833
SMILES:	NC(=O)C1C=C2C=CN=C(OCC3NC(=O)C(F)C3CC)C2=CC=1OC
Formula:	C₁₈H₂₀FN₃O₄
M.Wt:	361.3675
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	[1]. Lee KL, et al. Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fr

Description:

PF06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), and used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas.

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