BMS-986122 |CAS:313669-88-4 DC Chemicals

Cas No.:	313669-88-4
Chemical Name:	2-(3-bromo-4-methoxyphenyl)-3-[(4-chlorophenyl)sulfonyl]-thiazolidine
SMILES:	BrC1C=C(C2N(S(C3C=CC(Cl)=CC=3)(=O)=O)CCS2)C=CC=1OC
Formula:	C₁₆H₁₅BrClNO₃S₂
M.Wt:	448.782200098038
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	BMS-986122 is a potent positive allosteric modulator of μ-opioid receptor, significantly increases the inhibition of forskolin-stimulated adenylyl cyclase activity produced by an EC10 (30 pM) concentration of endomorphin-I in CHO-μ cells.
References:	References 1. Burford NT, et al. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10830-5. 2. Livingston KE, et al. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18369-74. 3. Livingston KE, et al. Mol Pharmacol. 2018 Feb;93(2):157-167. View Related Products by Target Opioid Receptor

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