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BRD9 Degrader-3

  Cat. No.:  DC67385   Featured
Chemical Structure
3033018-77-5
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More than 5000 active chemicals with high quality for research!
Field of application
BRD9 Degrader-3 (compound B20) is a highly potent molecular glue that induces targeted BRD9 degradation, demonstrating exceptional activity with a DC50 below 1.25 nM.
Cas No.: 3033018-77-5
Chemical Name: BRD9 Degrader-3
SMILES: FC1(/C=C(C#N)/C(N2C(C3=C(CC2)C(CN4CCN(CC4)CC5=C(OC)C=C(C(C(C)=C6C)=CN(C)C6=O)C=C5OC)=CC=C3)C)=O)CC1
Formula: C39H46FN5O4
M.Wt: 667.81
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC60948 NEK7 degrader (Compound 17) NEK7 degrader-1 is a NEK7 molecular glue degrader with a DC50 of 9  nM. NEK7 degrader-1 dose-dependently inhibits caspase-1 activity and IL-Ιβ release in macrophages in response to NLRP3 inflammasome activation. NEK7 degrader-1 can be used for autoinflammatory and autoimmune disorders like multiple sclerosis, neurodegeneraive diseases like Alzheimer's disease and cardiovascular and melabolic disorders like pericarditis and Type 2 diabetes research.
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