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SB405483

Cat. No.: DC67996 Featured

Chemical Structure

For research use only. We do not sell to patients.

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Field of application

SB-405483 is a specific small-molecule chemical compound used in scientific research as an allosteric ligand for the protein cereblon (CRBN). It is primarily a biochemical tool for studying protein degradation pathways and has potential implications for drug discovery.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:
Chemical Name:	SB405483
Synonyms:	SB405483; SB-405483; SB 405483
SMILES:	O=C(NC1=C(O)C=C(C#N)C=C1)NC(N=CC=C2)=C2OCC3=CC=CC=C3
Formula:	C₂₀H₁₆N₄O₃
M.Wt:	360.37
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	Dippon VN, et al. Identification of an allosteric site on the E3 ligase adapter cereblon. Nature. Published online January 21, 2026.

Cat. No.	Product name	Field of application
DC68076	BG-BRD4-P07
DC68075	BRU-SHP2-P06
DC68074	LLY-ESR1-P05
DC68073	AST-AR-P04
DC68072	NOV-EP001
DC68071	JHU-MDM2-P03
DC68070	CAS-FAK-P02
DC68069	MDA-S24-P01
DC68068	TB-008
DC68067	ARV-863

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.