Diphenylterazine (DTZ)|CAS 344940-63-2|DC Chemicals

Cas No.:	344940-63-2
Chemical Name:	Diphenylterazine
SMILES:	O=C1N2C(=C(NC(=C2)C2C=CC=CC=2)C2C=CC=CC=2)N=C1CC1C=CC=CC=1
Formula:	C₂₅H₁₉N₃O
M.Wt:	377.43
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	[1]. Yeh HW, et al. Red-shifted luciferase-luciferin pairs for enhanced bioluminescence imaging. Nat Methods. 2017 Oct;14(10):971-974. [2]. Hsien-Wei Yeh, et al. ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging. ACS Chem Biol.

Description:

Diphenylterazine is a bioluminescence agent.

In Vitro:

Diphenylterazine is a bioluminescence agent. Diphenylterazine alone yields very little background, leading to excellent signal-to-background ratios. Furthermore, Diphenylterazine elicits minimal cell toxicity at millimolar concentrations. Diphenylterazine injections into untransfected BALB/c mice do not yield any background emission. The bioluminescence resulting from intraperitoneally injected Diphenylterazine displays extended kinetics[1].

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