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Tesofensine(NS-2330)

  Cat. No.:  DC33111   Featured
Chemical Structure
195875-84-4
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More than 5000 active chemicals with high quality for research!
Field of application
Tesofensine (NS-2330) is a triple monoamine reuptake inhibitor inducing a potent inhibition of the re-uptake process in the synaptic cleft of the neurotransmitters dopamine (DA; IC50=6.5 nM), norepinephrine (NE;IC50=1.7 nM), and serotonin (5-HT;IC50=11 nM), and with potentials as an anti-obesity agent. Tesofensine is a CNS acting anti-obesity agent.
Cas No.: 195875-84-4
Chemical Name: Tesofensine
Synonyms: Tesofensine;(1R,2R,3S,5S)-3-(3,4-Dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8- azabicyclo[3.2.1]octane;NS 2330;(1S,3S,4R,5R)-3-(3,4-dichlorophenyl)-4-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane;(1R,2R,3S,5S)-3-(3,4-Dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo(3.2.1)octane;HY-14472;UNII-BLH9UKX9V1;tesofensina;(1R,2R,3S,5S)-3-(3,4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane;SCHEMBL37509;VCVWXKKWDOJNIT-ZOMKSWQUSA-N;NS00069658;Q7705544;DTXSID70905114;BLH9UKX9V1;(1R, 2R, 3S)-2-ethoxymethyl-3-(3,4-dichlorophenyl)tropane;TESOFENSINE (MART.);DB06156;NS2330;CHEMBL3989690;8-Azabicyclo(3.2.1)octane, 3-(3,4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-, (1R-(2-endo,3-exo))-;J-012675;TESOFENSINE [MI];Tesofensine [INN];MS-24909;(1R-(2-endo,3-exo))-3-(3,4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo(3,2,1)octane-2-hydroxy-1,2,3-propanetricarboxylate;TESOFENSINUM;DA-58430;NS-2330;AKOS027326890;195875-84-4;TESOFENSINE [MART.];CS-0003378;(1R,2R,3S)-2-ethoxymethyl-3-(3,4-dichlorophenyl)tropane;G87045;TESOFENSINE [WHO-DD]
SMILES: CCOC[C@@H]1[C@H](C[C@@H]2CC[C@H]1N2C)C3=CC(=C(C=C3)Cl)Cl
Formula: C17H23NOCl2
M.Wt: 328.27662
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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