| Cas No.: | 1003000-59-6 |
| Chemical Name: | 1-(2-(trityloxy)ethyl)guanidine |
| Synonyms: | NY 0116 |
| SMILES: | N(CCOC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)C(=N)N |
| Formula: | C22H23N3O |
| M.Wt: | 345.446 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | NY0116 (NY 0116) is a small molecule neuromedin U receptor 2 (NMUR2) with EC50 of 27.76 uM for hNMUR1 and 13.61 uM for hNMUR2 in intracellular calcium mobilization assays; decreases cAMP while stimulating calcium signaling in stably expressing NMUR2 HEK293 cells; significantly decreased high-fat diet consumption in vivo after acute administration, decreased body weight and more specifically, decreased the percentage of visceral adipose tissue (VAT) in obese mice after repeated administration. |

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