| Cas No.: | 1003000-60-9 |
| Chemical Name: | 1-(3-(trityloxy)propyl)guanidine |
| Synonyms: | NY 0128 |
| SMILES: | N(CCCOC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)C(=N)N |
| Formula: | C23H25N3O |
| M.Wt: | 359.473 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | NY0128 (NY 0128) is a small molecule neuromedin U receptor 2 (NMUR2) with EC50 of 29.99 uM for hNMUR1 and 10.30 uM for hNMUR2 in intracellular calcium mobilization assays; decreases cAMP while stimulating calcium signaling in stably expressing NMUR2 HEK293 cells; significantly decreased high-fat diet consumption in vivo after acute administration, decreased body weight and more specifically, decreased the percentage of visceral adipose tissue (VAT) in obese mice after repeated administration. |

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