Pamabrom|CAS 606-04-2|DC Chemicals

Cas No.:	606-04-2
Chemical Name:	Pamabrom
Synonyms:	Pamabrom;8-BROMOTHEOPHYLLINE COMPOUND WITH 2-AMINO-2-METHYL-1-PROPANOL (1:1);2-amino-2-methylpropanol 8-bromotheophyllinate;PAMABROM,USP;2-azanyl-2-methyl-propan-1-ol;8-bromo-1,3-dimethyl-7H-purine-2,6-dione;8-bromo-1,3-dimethyl-7H-purine-2,6-quinone;2-AMino-2-Methyl-1-propanol 8-broMotheophyllinate;2-amino-2-methylpropan-1-ol,8-bromo-1,3-dimethyl-7H-purine-2,6-dione;8-Brom-1,3-dimethyl-3,7-dihydro-purin-2,6-dion,Verbindung mit 2-Amino-2-methyl-propan-1-ol;8-bromo-1,3-dimethyl-3,7-dihydro-purine-2,6-dione,compound with 2-amino-2-methyl-propan-1-ol;8-bromo-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione;Predema;Premsyn PMS;Sunril;UNII-UA8U0KJM72;8-Bromotheophylline 2-Amino-2-methyl-1-propanol;2-Amino-2-methylpropanol 8-bromotheophyllinate
SMILES:	OCC(N)(C)C.BrC1=NC2N(C(N(C(=O)C=2N1)C)=O)C
Formula:	C₁₁H₁₈BrN₅O₃
M.Wt:	348.19632101059
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Pamabron is a common over-the-counter diuretic used for relief of menstrual-associated symptoms. The active diuretic ingredient in pamabrom is 8-bromotheophylline. Pamabrom is available in combination with acetaminophen (paracetamol) for various conditions such as back pain and menstrual relief. The acetaminophen helps reduce menstrual pains and the pamabrom reduces associated bloating.

References:

[1]. Ortiz MI, Rangel-Flores E, Carrillo-Alarcón LC, et al. Prevalence and impact of primary dysmenorrhea among Mexican high school students. Int J Gynaecol Obstet. 2009 Dec;107(3):240-3. [2]. Swanson JK, English JC 3rd. Serum sickness-like reaction to Pamabrom. J Drugs Dermatol. 2006 Mar;5(3):284-6. [3]. Di Girolamo G, Sánchez AJ, De Los Santos AR, et al. Is acetaminophen, and its combination with pamabrom, an effective therapeutic option in primary dysmenorrhoea? Expert Opin Pharmacother. 2004 Mar;5(3):561-70. [4]. Pamabrom

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