QQN52061|CAS 907952-06-1|DC Chemicals

Cas No.:	907952-06-1
Chemical Name:	N-[(2E)-3-(4'-Chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)tyrosine
Synonyms:	QQN52061; QQN-52061; QQN 52061;
SMILES:	O=C(O)[C@H](CC1=CC=C(OCC2=CC=CC=C2)C=C1)NC(/C=C/C3=CC=C(C4=CC=C(Cl)C=C4)C=C3)=O
Formula:	C₃₁H₂₆ClNO₄
M.Wt:	512.002
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	QQN52061 is a GPR34 receptor antagonist. GPR34 receptor antagonist 2 can be used for immune diseases, inflammatory diseases research[1].
Target:	GPR34 receptor[1]
In Vitro:	Endogenous ligands of GPR34, a G protein-coupled receptor, act on histamine-releasing activity on antigen- or concanavalin A-stimulated rat mast cells and synergize with nerve growth factor on rat mast cells. It is a lipid such as lysophosphatidylserine having the activity of releasing histamine. GPR34 antagonists can be used, for example, for histamine release inhibitors, immune diseases, edema, hyperacidity, etc[1].
References:	[1]. Fumio Ito, et al. Agent for controlling function of gpr34 receptor. WO2006088246 A1.

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