| Cas No.: | 188804-07-1 |
| Chemical Name: | Benzenepropanoic acid, beta-[[2-[[3-[(aminoiminomethyl)amino]benzoyl]amino]acetyl]amino]-3,5-dichloro- |
| Synonyms: | SC68448 |
| Formula: | C19H19Cl2N5O4 |
| M.Wt: | 452.292 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | SC-68448 (SC68448) is a potent, selective peptidomimetic antagonist of the integrin αvβ3 with IC50 of 1 nM, 100-fold selectivity over αIIbβ3; inhibits alpha(v)beta3-mediated endothelial cell proliferation in a dose-dependent manner but did not inhibit tumor cell proliferation in cell-based assays; inhibits angiogenesis in vivo in a basic fibroblast growth factor-induced rat corneal neovascularization model. |

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