TG003|CAS 300801-52-9|DC Chemicals

Cas No.:	300801-52-9
Chemical Name:	(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one
Synonyms:	2-Propanone,1-(3-ethyl-5-methoxy-2(3H)-benzothiazolylidene)-;(Z)-1-(3-Ethyl-5-methoxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one;1-(3-ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-Propanone;CDC2-LIKE KINASE INHIBITOR, TG003;TG003;(1Z)-1-(3-Ethyl-5-methoxy-1,3-benzothiazol-2(3H)-ylidene)acetone;(1Z)-1-(3-Ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one;2-Propanone, 1-(3-ethyl-5-methoxy-2(3H)-benzothiazolylidene)-, (1Z)-;(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one;TG 003;Cdc2-Like kinase inhibitor;Clk inhibitor;Clk Inhibitor, TG003;MLS000077198;GTPL5942
SMILES:	COC1C=C2N(CC)\C(=C\C(C)=O)SC2=CC=1
Formula:	C₁₃H₁₅NO₂S
M.Wt:	249.3287
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor with IC50 of 20 nM, 200 nM, and 15 nM for Clk1, Clk2, and Clk4, respectively. No inhibitory effect on Clk3, SRPK1, SRPK2, or PKC.

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