VU0466551|VU 0466551;VU-0466551

Cas No.:	1448705-06-3
Chemical Name:	VU-0466551
Synonyms:	VU0466551;1-(1-Benzyl-3-methyl-1H-pyrazol-5-yl)-3-(3,4-difluorophenyl)urea;BDBM50437979
SMILES:	FC1=C(C=CC(=C1)NC(NC1=CC(C)=NN1CC1C=CC=CC=1)=O)F
Formula:	C₁₈H₁₆F₂N₄O
M.Wt:	342.342650413513
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

VU0466551 (VU-0466551) is a potent, selective, small-molecule GIRK activator with EC50 of 70.6 nM (GIRK1/2 channels); demonstrates analgesic effects when dosed alone or in combination with sub-maximally effective doses of morphine.

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